Jonathan Comeau, Ph.D. Student

Details: Jonathan Comeau, Ph.D. Student

Email: jcamea2@po-box.mcgill.ca
Location: McGill University
Montreal - QC - H3A 2T8

Research : Development of two-photon ICCS
(Co-advisors: Paul Wiseman - Réal Vallée)

Jonathan Comeau focuses on the development and characterization of Image Cross-Correlation Spectroscopy (ICCS), a technique whereby multiple fluorescent species are correlated in time and space to reveal any interactions present as well as providing quantitative dynamic measurements. ICCS is well suited for studying adhesion structure formation in living cells, which is an important process in both cell mobility and signaling. Development of ICCS could lead to answers to many biological questions that would otherwise be difficult to obtain by other techniques.

PUBLICATIONS

Costantino S., Comeau J.W.D., Kolin D.L. & Wiseman P.W. (2005) Accuracy and Dynamic Range of Spatial Image Correlation and Cross-Correlation Spectroscopy. Biophys. J. 89, 1251–1260

MEETINGS

Comeau, J.W.D., Costantino, S., Wiseman, P.W. (2005) A comparison of techniques that measure biomolecular colocalization: image correlation and standard statistical image analysis 49th annual meeting of the Biophysical. Society, Long Beach, CA.

Comeau, J.W.D., Bachir, A.I., Wiseman, P.W. (2003) Simulation modeling of image correlation spectroscopy with comparison to measurements on living cells. Chemical Biophysics Symposium 2003. Toronto, ON.